01 - In a large bowl, whisk together buttermilk, egg, garlic powder, onion powder, paprika, salt, and black pepper. Add chicken tenders and toss to coat. Let marinate for at least 15 minutes or up to 2 hours for enhanced flavor.
02 - In a separate shallow dish, mix flour, panko breadcrumbs, paprika, salt, and black pepper until evenly combined.
03 - Remove chicken tenders from marinade, allowing excess to drip off. Dredge each piece thoroughly in the flour mixture, pressing gently to ensure coating adherence.
04 - Heat vegetable oil in a deep skillet or pot to 350°F (175°C) for deep frying.
05 - Fry chicken tenders in batches for 3 to 4 minutes per side, or until golden brown and cooked through (internal temperature should reach 165°F / 74°C).
06 - Transfer fried tenders to a paper towel-lined plate to drain excess oil. Serve hot with preferred dipping sauces.