01 - Combine buttermilk and hot sauce in a large bowl. Submerge chicken pieces completely, cover, and refrigerate for minimum 30 minutes up to 8 hours for optimal tenderness.
02 - Whisk together flour, paprika, garlic powder, onion powder, salt, black pepper, and cayenne in a shallow bowl until thoroughly combined.
03 - Remove chicken from buttermilk marinade, allowing excess liquid to drip off. Press each piece firmly into seasoned flour mixture, ensuring complete coating. Transfer to wire rack.
04 - Heat 1 inch vegetable oil in heavy skillet to 350°F. Fry chicken in batches without overcrowding, cooking 8–12 minutes per side until golden brown and internal temperature reaches 165°F. Drain on paper towels.
05 - Preheat oven to 425°F. Whisk flour, baking powder, baking soda, salt, and sugar. Cut in cold butter using pastry blender until mixture resembles coarse crumbs. Stir in buttermilk until dough just comes together.
06 - Turn dough onto floured surface, pat gently to 1-inch thickness. Cut rounds using biscuit cutter. Place on baking sheet, brush tops with buttermilk, bake 12–15 minutes until golden brown.
07 - Melt butter over medium heat in saucepan. Whisk in flour, cook 2 minutes while stirring. Gradually add milk, whisking constantly for 5–7 minutes until thickened. Season with black pepper and salt.
08 - Plate freshly fried chicken alongside warm biscuits. Generously ladle hot pepper gravy over chicken and biscuits. Serve immediately while hot.