01 - Combine cranberries, orange juice, sugar, orange zest, and salt in a small saucepan. Simmer over medium heat, stirring occasionally, until cranberries burst and sauce thickens, about 8 to 10 minutes. Remove from heat and allow to cool.
02 - In a large bowl, gently mix ground turkey, chopped onion, garlic, parsley, Dijon mustard, Worcestershire sauce, salt, pepper, and breadcrumbs until just combined. Shape into 4 equal-sized patties.
03 - Heat olive oil in a large skillet over medium heat. Cook patties for 5 to 6 minutes per side until golden brown and cooked through, reaching an internal temperature of 165°F.
04 - Lightly toast the burger buns, if desired.
05 - Place lettuce on bottom half of each bun, top with turkey patty, spoon cranberry sauce over patties, then add sliced tomatoes and red onion. Cover with top bun half.
06 - Serve immediately, offering extra cranberry sauce on the side if preferred.